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First Smile Pediatric Dentistry

Pediatric dentist
5.0 (463 reviews) Updated May 02, 2026
250 E Yale Loop Ste 205, Irvine, CA 92604

About First Smile Pediatric Dentistry

Pediatric dentistry occupies a unique space in healthcare—it’s where tiny teeth meet big milestones. From the first toothbrush battles to the triumph of a cavity-free checkup, these offices specialize in making dental care approachable for kids (and reassuring for parents). Irvine’s mix of young families and tech-savvy residents means demand for providers who understand both preventive care and the occasional emergency lollipop mishap. The city’s planned communities and school districts create a steady need for services like sealants, fluoride treatments, and early orthodontic screenings—all delivered with an awareness that a child’s experience today shapes their dental habits tomorrow.

On East Yale Loop, just north of the 405’s hum, First Smile Pediatric Dentistry fits into the professional landscape of Irvine’s medical corridor. The Suite 205 location places it among other healthcare practices, making it a practical stop for families already running errands or shuttling between appointments in the area. Pediatric dentists here handle everything from infant oral exams to sports mouthguards, bridging the gap between medical necessity and the realities of childhood—think loose teeth at recess or the aftermath of a birthday cake binge. Questions about thumb-sucking, teething timelines, or when to schedule that first visit? Those are the daily conversations happening in offices like this one.

Logistics for new patients usually start with a call to (949) 299-1111, where someone can outline what to expect—whether it’s a toddler’s introductory “ride” in the dental chair or a teen’s wisdom teeth consultation. The map pinpoints the office between the freeway and UC Irvine’s sprawl, a location that’s as central as it gets in this part of Orange County. And while no one *likes* dental visits, the right provider can at least make them forgettable—for all the right reasons.

This listing was last updated on May 02, 2026

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Business Hours

Business Details

Accessibility
Wheelchair accessible entrance
Wheelchair accessible parking lot
Wheelchair accessible restroom
Offerings
Emergency services
Pediatric care
Sedation dentistry
Amenities
Restroom
Planning
Appointment required
Appointments recommended
Payments
Credit cards
Debit cards
NFC mobile payments
Payment plans