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My Smile Preston

Dental clinic
3.9 (26 reviews) Updated Apr 17, 2026
5010 Preston Hwy #100, Louisville, KY 40213

About My Smile Preston

Dental clinics often feel like a necessary stop rather than a place you’d recommend to friends. Yet when the right one clicks, it’s usually because the basics are handled without fuss—cleanings, fillings, check-ups, and the occasional emergency. My Smile Preston fits that mold for people in the South Louisville area. They cover routine care, cosmetic tweaks like whitening or veneers, and even minor oral surgeries, all under one roof.

The office sits at 5010 Preston Hwy #100, Louisville, KY 40213, tucked between the I-264 interchange and a cluster of neighborhood shops. That stretch of Preston Highway sees steady traffic, so parking isn’t the usual downtown hassle. If you’ve ever driven past the Watterson Expressway exit, you’ve likely passed it without realizing—those low-slung brick buildings blend into the landscape until you need them.

Questions about availability or specific treatments can be sorted by calling (502) 966-5252. For directions, pull up the map on your phone before heading out. The area around Preston Highway has that quiet, workaday rhythm—no tourist crowds, just locals getting things done.

This listing was last updated on April 17, 2026

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Business Hours

Business Details

Accessibility
Wheelchair accessible entrance
Wheelchair accessible parking lot
Wheelchair accessible restroom
Offerings
Cosmetic dentistry
Amenities
Restroom
Planning
Appointment required
Appointments recommended
Payments
Credit cards
Debit cards
NFC mobile payments
Payment plans