Directory Only — This site does not provide medical or health advice. Listings contain publicly available business information. Always consult a qualified dental professional for any health-related concerns.

Dr. Joseph E. Margarone III, DDS

Oral surgeon
3.9 (77 reviews) Updated Mar 31, 2026
6490 Main St #3 Williamsville, NY 14221, Buffalo

About Dr. Joseph E. Margarone III, DDS

Oral surgery occupies that quiet but essential corner of healthcare—neither the routine checkups of a general dentist nor the high-visibility work of cosmetic specialists. It’s the kind of practice you might not think about until you need it: wisdom teeth that refuse to cooperate, implants that require precision, or jaw realignment that demands a specialist’s hand. These procedures don’t advertise themselves with flashy signs or social media campaigns. Instead, they rely on the kind of word-of-mouth that spreads between dentists’ offices and patients who’ve been through the process themselves.

On Main Street in Williamsville, just east of the village’s central stretch, Dr. Joseph E. Margarone III, DDS maintains an oral surgery practice at 6490 Main St #3. The suite number suggests a professional building—no storefront fanfare, just a discreet entrance for those arriving with referrals in hand. Appointments here likely start with a consultation, followed by whatever the case requires: extractions, bone grafting, or corrective procedures that bridge the gap between dental work and medical necessity. When it’s time to schedule, the office fields calls at (716) 631-2800, a number that connects to the same quiet efficiency as the practice itself.

Williamsville’s Main Street carries a mix of medical offices, local businesses, and the occasional chain outpost, all strung along a corridor that’s equal parts functional and forgettable. The oral surgeon’s location fits the pattern—no scenic views or historic charm, just a place where the work happens without preamble. For those mapping their route, the directions confirm what the address implies: a stop designed for purpose, not spectacle.

This listing was last updated on March 31, 2026

Patient Reviews (0)

Sign in to leave a review.

No reviews yet. Be the first to review!

Business Hours

Business Details

Accessibility
Wheelchair accessible entrance
Wheelchair accessible parking lot
Wheelchair accessible restroom
Amenities
Restroom
Planning
Appointment required
Appointments recommended
Payments
Credit cards
Debit cards
NFC mobile payments