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Signature Smiles Dentistry

Dental clinic
4.9 (382 reviews) Updated May 04, 2026
2200 Space Park Dr #300, Houston, TX 77058

About Signature Smiles Dentistry

Just off NASA Parkway, where Houston’s aerospace heritage hums in the background, Signature Smiles Dentistry fits into the professional rhythm of the Space Park area. The clinic occupies suite 300 at 2200 Space Park Dr, a spot that’s as convenient for Clear Lake residents as it is for those working in the nearby tech and engineering corridors. Dental care here covers the essentials—from routine cleanings and fillings to more involved procedures like crowns and bridges—without the frills of a spa-like experience.

Dental clinics in this part of town tend to cater to busy schedules, and this one follows that practical approach. Whether it’s a quick checkup or addressing a persistent toothache, the focus remains on efficiency and standard care. Questions about insurance coverage or appointment availability are best directed to the front desk, where staff can be reached at (281) 333-3406 during business hours. Unlike some practices that emphasize cosmetic upgrades, the services here lean toward maintenance and repair, reflecting the no-nonsense vibe of the surrounding industrial and office parks.

The building itself is part of a larger complex that houses a mix of medical and professional offices, so parking and access are straightforward. For first-time visitors, pulling up the map beforehand can save a minute or two of circling—suite numbers aren’t always obvious from the street. It’s the kind of place you’d bookmark for a filling or an emergency, then forget about until the next reminder from your calendar.

This listing was last updated on May 04, 2026

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Business Hours

Business Details

Accessibility
Wheelchair accessible entrance
Wheelchair accessible parking lot
Wheelchair accessible restroom
From the business
Identifies as women-owned
Service options
Onsite services
Offerings
Cosmetic dentistry
Emergency services
Pediatric care
Sedation dentistry
Amenities
Restroom
Planning
Appointment required
Appointments recommended
Payments
Credit cards
Debit cards
NFC mobile payments
Payment plans